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| Advisor(s) | apt. Angga Nugraha Sanjaya, S.Farm., M.Farm. | |
| Author(s) | MUSTAQFIRAH, IMA | |
| Issued Date | 2026 | |
| Abstract | Chronic Kidney Disease (CKD) is a progressive disease that requires long-term pharmacological therapy and regular hemodialysis to maintain patients’ quality of life. Poor adherence to pharmacological therapy may reduce treatment effectiveness, increase the risk of complications, and worsen patients’ quality of life. This study is aimed to analyze the relationship between pharmacological therapy adherence and quality of life among chronic kidney disease patients undergoing hemodialysis at Sembiring General Hospital, Deli Tua. The study employed a quantitative correlational design involving 50 chronic kidney disease patients undergoing hemodialysis. Data were collected using the Morisky Medication Adherence Scale-8 (MMAS-8) and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaires. The data were analyzed using univariate analysis, Spearman’s rank correlation, the Mann–Whitney U test, and the Kruskal–Wallis test. The results showed a significant positive relationship between pharmacological therapy adherence and quality of life (r = 0.883; p < 0.001). Age was negatively associated with therapy adherence (r = −0.813; p < 0.001), while educational level was significantly associated with therapy adherence (p = 0.017). In contrast, sex (p = 0.547) and occupation (p = 0.322) were not significantly associated with therapy adherence. In addition, the physical, psychological, social, and environmental domains of quality of life were positively associated with pharmacological therapy adherence. It was concluded that better pharmacological therapy adherence was associated with better quality of life among chronic kidney disease patients undergoing hemodialysis. Toward patient education, regular adherence monitoring, and support from healthcare professionals and family members are recommended to improve therapy adherence and enhance patients’ quality of life. Keywords: Chronic Kidney Disease, Hemodialysis,Pharmacological Therapy Adherence, Quality of Life | 1 |
| Item Type | Skripsi | |
| Keywords | Penyakit Ginjal Kronis,(Chronic Kidney Disease),Hemodialisis,(Hemodialysis), Kepatuhan Terapi Farmakologi,(Pharmacological Therapy Adherence), Kualitas Hidup, (Quality of Life). | 1 |
| Collection | Fakultas Farmasi, S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 13-08-2026 | |
| Updated Date | 13-08-2026 | |
| URI | https://repo.delihusada.mediantarakreasindo.com/handle/123456789/10865 | |
| File |
2218084_IMAMUSTAQFIRAH_SKRIPSI_S1.pdf
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