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| Advisor(s) | No advisor | |
| Author(s) | WIDIA FITRI PASARIBU | |
| Issued Date | 2026 | |
| Abstract | Torch ginger (Etlingera elatior) is a plant containing secondary metabolites with potential as a natural antioxidant. This study aimed to formulate torch ginger flowers and leaves into nanosimplicia in the form of brewed tea and compare their antioxidant activities. This research was a laboratory experimental study. The flower and leaf samples were dried and processed into simplicia, followed by simplicia characterization and phytochemical screening. Nanosimplicia were prepared using the sonication method at concentrations of 10%, 15%, and 20%. Characterization of the nanosimplicia included particle size, zeta potential, and polydispersity index using a Particle Size Analyzer (PSA). The brewed tea preparations were evaluated for organoleptic properties, yield, weight uniformity, pH, solubility, and leakage. Antioxidant activity was determined using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method and expressed as IC₅₀ values. Antioxidant activity data were statistically analyzed using One-Way ANOVA. The results showed that the flower and leaf nanosimplicia had particle sizes ranging from 100.333–293.667 nm and zeta potential values ranging from 30.267–35.433 mV and met the preparation evaluation parameters. Phytochemical screening showed the presence of flavonoids, alkaloids, saponins, tannins, and steroids/triterpenoids in both flower and leaf simplicia. The highest antioxidant activity was obtained from the F1 leaf nanosimplicia formula, with an IC₅₀ value of 0.17, while the best flower nanosimplicia formula had an IC₅₀ value of 0.24. The One-Way ANOVA results showed a significant difference among the formulas (p<0.05). Further research is recommended to develop flower and leaf nanosimplicia into transdermal preparations and to identify the active compounds using LC-MS/LC-HRMS. | 1 |
| Item Type | Skripsi | |
| Keywords | Antioksidan (Antioxidant), 2,2-Difenil-1-pikrilhidrazil (DPPH) (2,2-Diphenyl-1-picrylhydrazyl (DPPH)), Etlingera elatior (Etlingera elatior), Nanosimplisia (Nanosimplicia), Teh Seduhan (Brewed Tea) | 1 |
| Collection | S1-Farmasi | |
| Publisher | INSTITUT KESEHATAN DELI HUSADA | |
| Submitted Date | 27-10-2026 | |
| Updated Date | 27-10-2026 | |
| URI | No URI | |
| File |
2218230_WIDIAFITRIPASARIBU_SKRIPSI_S1.pdf
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